As a child, Barry Allen's life was uprooted forever by the death of his mother. The police arrested his father for the crime, but Barry had seen a Strange Man with inhuman powers in a yellow suit commit the deed.
The death drove him to find answers, researching cases of paranormal activity and possible superhuman forces at work. He also found answers in science, getting a job as an intern with the Central City PD Crime Scene Unit. However, he was perpetually late.
Hearing about the Starling City vigilante, he looked into the stories about him, keeping a running tally of the colorful criminals he caught. He followed and developed theories as to the man's operations. When a seemingly impossible case cropped up in Starling City, Allen used deferred sick days to travel across country, claiming that this case connected to something happening in Central City and inserting himself into the investigation.
He proved instrumental to solving the case, even meeting the vigilante and learning his secret identity. Parting with the man on cordial terms, he returned to his duties...mere seconds before Central City's new particle accelerator backfired, showering the city with exotic radiation. In the ensuing confusion, Allen was struck by lightning, but survived. Allen was in a coma for 9 months. During the time he was in a coma, he was moved to S.T.A.R. Labs. He awoke from his coma and met Cisco Ramon and Caitlin Snow.
He later would later join them in addition to Harrison Wells as part of Team Flash. Later he encounters with numerous Metahumans and Villains, such as, Captain Cold, Heat Wave, but, he would encounter The Man in the Yellow Suit who killed his mother.